The decision to be part of a clinical trial isn’t an easy one, but it’s an especially hard decision for parents. Thousands of families agreed to allow their premature babies to take part in a government-funded study. Now, a federal agency has found that a number of major universities failed to tell them that the study of oxygen levels for their very premature babies could cause blindness or death. The study’s designers say that the risk of blindness should have been more clearly explained, but that the infants were within the standard of care. Others say the lack of disclosure was unethical. Diane and guests discuss balancing the risks and benefits of clinical trials.